Ourcustom biotinylation services for peptides and proteins is based on our biotinylation technology that was developped to yield biologically active peptides. Standard biotinylation methods often result in non-active peptides because the relevant amino acid side-chains are blocked by biotinylation. Initially the metod was developped for Insulin-like growth factors (IGF´s) and analogs. Biotinylated IGF´s and analogs bind to antibodies, Insulin-like Growth Factor Binding-Proteins and their receptors. They are biologically active in-vitro and in-vivo. Applications are development of immunoassays, ligand based assay formats and experimental cell therapy.

Examples and references to scientific papers are found in:

IGF004: Applications of biotinylated IGF´s and analogs

IGF015: Applications of Biotinylated (Biotin-labeled) IGFBP´s.

The price for one custom biotinylation is 286.- Euro plus VAT (VAT is applicable in Europe only) and freight cost. It includes biotinylation of a minimum of 20 µg and a maximum of 100 µg of a peptide or a protein, purification by size exclusion chromatography and lyophilization. For larger quantities of up to 1 mg the price is 390.- Euro plus VAT (in Europe only) and freight cost. For custom biotinylation we cannot give any guarantee on biological or other activities.

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