Product specifications monoclonal mouse anti-human CD40:

Description: IgG fraction from mouse monoclonal antibody (clone 2G8/E5) obtained by immunization of mice with human CD40. The IgG fraction was purified using Protein G-Sepharose.

Isotype: IgG1.

Storage: Store at -20°C.

Stability: Stable for at least one year. Avoid repeated freezing and thawing.

Applications: This antibody can be used in ELISA and flow cytometry studies. It recognizes CD40, a 50 kDa glycoprotein, member of the TNF receptor family, expressed on antigen-presenting cells such as B cells, macrophages, dendritic cells and thymic epithelial cells and overexpressed in a broad range of leukemias, lymphomas and carcinomas. CD40 is activated by gp39 and may stimulate cell growth, differentiation or death.

Formulation: Solution at 1.0 mg/ml in PBS.

References :

Foy, T.M. et. al. (1996) Annu. Rev. Immunol. 14, 591 - 617.

Eliopoulos, A.G. & Young, L.S. (2004) Curr. Opin. Pharmacol. 4, 360 - 367.

Werneburg, B. et. al. (2001) J. Biol. Chem. 276, 43334 - 43342.

 Datasheet for Anti-Human CD40 monoclonal, mouse