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Antibodies for Transcription Research
Anti-human Suppressor of RNA Polymerase B (SRB7) , monoclonal, mouse
Clone 5G12/H8
Product Specifications Anti-human Suppressor of RNA Polymerase B (SRB7) IgG fraction(monoclonal):
Description: IgG fraction from mouse monoclonal antibody (clone 5F10/D11) obtained by immunization of mice with a recombinant human SRB7 (15 kDa). The IgG fraction was purified using Protein G-Sepharose.
Isotype: IgG2b.
Storage: Store at -20°C.
Stability: Stable for at least one year. Avoid repeated freezing and thawing.
Applications: This antibody can be used in ELISA assays (1: 8,000 dilution) and Western blot (1: 8,000 dilution)). It recognizes human SRB7, an essential component of SRB7/MED-containing cofactor complex (SMCC). This complex associates with the RNA polymerase II holoenzyme through SRB7 to enhance the gene-specific activation or repression induced by DNA-binding transcription factors.
Formulation: Solution at 0.5 mg/ml in PBS.
Datasheet for Anti-human Suppressor of RNA Polymerase B (SRB7) , monoclonal, mouse